International migration and its consequence effects in developing countries has become an integral global issue. In every day, more people are migrating from the developing to developed countries of the world due to the socio-economic inequality that exist between these two spaces, to the advantage of the developed countries. As the labour markets in the developing countries offer lesser opportunities, increase in the movement of skilled and professional skilled labour to developed countries becomes highly intensified. This paper focuses on migration and its implications on brain drain in developing countries. The paper was anchored on push-pull theory of migration. Data used in this paper were obtained from books, journal articles, government records/statistics, news letter, and internet websites and were analysed using content analysis. The paper explored the causes of skilled and professional skilled labour migration in developing countries. It also examined socio-economic impacts of brain drain on immigrants and sending countries‟ economies. In conclusion, it highlights a few policy recommendations for better working conditions and pay of skilled and professional skilled labour in developing countries.