The study examines the effect of taxation on economic growth in Nigeria between 1993 and 2019. The study employed Dynamic Ordinary Least Square and Johansen co-integration to capture the objective. The result indicated that a long-run relationship existed among the variables. The coefficient indicated that Custom and Excise Duties were harmful to economic growth. Similarly, Value Added Tax was equally negatively related to Gross Domestic Product such that 1% increase in Value Added Tax collected led to 1.15% decrease in growth. The other form of taxes Company Income Tax amnd Petroleum Profit Tax contributed substantially to economic growth. The study discovered that two taxes (VAT, CED) did not contribute positively to the economic growth while the other independent variables (CIT, PPT) contributed positively to the economic growth. Based on these findings, the study recommends that, for a nation to grow, especially in Nigeria, the government's focus should be on some taxes that need to be improved significantly to aid economic growth. Primarily, on VAT and CED, policies should be geared towards them for positive effectiveness so as to improve the economic activities in Nigeria, which will in turn create a better avenue for actualizing economic growth.