In recent times more attention is given to the interrelationship among economic growth, globalization and environmental quality such as Carbon Dioxide (CO2) emissions in quest to ensure Sustainable Development and the challenge posed by climate change. Prior studies have focused on how trade component in globalization influences the environment. However, recent studies posit that other aspect of globalization such as economic, social, and political are also important, the integration of which needs to be considered in sustainable development. Thus, this paper enriches current literature by providing new evidence derived from a comprehensive globalization index to confirm the long- and short-term relationship among economic growth, globalization and the environment in Nigeria. This study used the KOF globalization index as the proxy for globalization, per capita GDP as proxy for economic growth and CO2 emissions as the proxy for the environment. The data on globalization index was retrieved from KOF Swiss Economic Institute while those of per capita GDP and CO2 emissions were obtained from the World Bank for the period 1990 to 2023 and employed autoregressive distributed lags (ARDL) estimation technique. The empirical results indicate that the nexus among economic growth, globalization and the environment is cointegrated in the long-term. In the short - and long - run, the study found that economic growth and globalization improve the environment i.e causing reduction in environmental degradation. The finding also showed that consumption of renewable energy, adherence to rule of law and international price of crude oil as determinants of environmental quality in Nigeria. The study recommends that government should be concerned about environmental development when promoting globalization through economic and social activities. Moreso, policymakers should continue to encourage in investment in renewable energy as energy-intensive industries are the major source of CO2 emissions in Nigeria.